Journal article
Antigen-induced Lung Solute Clearance in Rats Is Dependent on Capsaicin-sensitive Nerves
Abstract
Chemosensitive sensory nerves have an important effector role in the control of vascular permeability in rat airways after neurogenic inflammation. To investigate whether they also have a role in antigen-induced lung inflammation, we have studied the changes in lung solute clearance (LSC) in sensitized rats after aerosol challenge with allergen and the effect of prior capsaicin-induced denervation on these changes. Sprague-Dawley rats were …
Authors
Sestini P; Dolovich M; Vancheri C; Stead RH; Marshall JS; Perdue M; Gauldie J; Bienenstock J
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 139, No. 2, pp. 401–406
Publisher
American Thoracic Society
Publication Date
February 1989
DOI
10.1164/ajrccm/139.2.401
ISSN
1073-449X