Journal article
VARIATION IN THE DISPOSITION OF MORPHINE AFTER I.M. ADMINISTRATION IN SURGICAL PATIENTS
Abstract
The disposition of morphine when administered by i.m. injection was studied in 36 patients receiving morphine as part of premedication before general anaesthesia, and in five patients who received morphine as a postoperative analgesic after median sternotomy for coronary artery surgery (PCA group). Maximum plasma concentration of morphine (CP max) was 75.3 +/- 6.0 (mean elimination rate constant (k) 4.85 X 10(-3) min-1 and half-life (T1/2) = …
Authors
RIGG JRA; BROWNE RA; DAVIS C; KHANDELWAL JK; GOLDSMITH CH
Journal
British Journal of Anaesthesia, Vol. 50, No. 11, pp. 1125–1130
Publisher
Elsevier
Publication Date
November 1978
DOI
10.1093/bja/50.11.1125
ISSN
0007-0912