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Lymphoid tissues induce NGF‐dependent and...
Journal article

Lymphoid tissues induce NGF‐dependent and NGF‐independent neurite outgrowth from rat superior cervical ganglia explants in culture

Abstract

Induction of neurite outgrowth from superior cervical ganglia (SCG) by rat lymphoid tissues was studied using a tissue culture model. Neonatal rat SCG were cultured with 6-12-week-old rat thymus, spleen, or mesenteric lymph node (MLN) explants in a Matrigel layer, in defined culture medium without exogenous nerve growth factor (NGF). SCG were also co-cultured with neonatal rat heart (as positive control) or spinal cord (SC; as negative …

Authors

Kannan Y; Stead RH; Goldsmith CH; Bienenstock J

Journal

Journal of Neuroscience Research, Vol. 37, No. 3, pp. 374–383

Publisher

Wiley

Publication Date

February 15, 1994

DOI

10.1002/jnr.490370309

ISSN

0360-4012