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Validation of MRI predictors of multiple sclerosis...
Journal article

Validation of MRI predictors of multiple sclerosis diagnosis in children with acute CNS demyelination

Abstract

BACKGROUND: In a recent Canadian prospective study of children with acute demyelinating syndromes (ADS), we demonstrated that the presence of T2 periventricular and T1-hypointense lesions predicted MS diagnosis. We aimed to validate these predictors in a Dutch cohort of children with ADS. METHODS: Participants with ADS were identified from a prospective cohort or archived dataset. MS was diagnosed based on clinical or MRI evidence of relapsing …

Authors

Verhey LH; van Pelt-Gravesteijn ED; Ketelslegers IA; Neuteboom RF; Catsman-Berrevoets CE; Feldman BM; Streiner DL; Sled JG; Hintzen RQ; Banwell B

Journal

Multiple Sclerosis and Related Disorders, Vol. 2, No. 3, pp. 193–199

Publisher

Elsevier

Publication Date

July 2013

DOI

10.1016/j.msard.2012.12.003

ISSN

2211-0348