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A systematic review of discontinued trials...
Journal article

A systematic review of discontinued trials suggested that most reasons for recruitment failure were preventable

Abstract

OBJECTIVE: To collect and classify reported reasons for recruitment failure in discontinued randomized controlled trials (RCTs) and to assess reporting quality. METHODS: We systematically searched MEDLINE and EMBASE (2010-2014) and a previous cohort of RCTs for published RCTs reporting trial discontinuation due to poor recruitment. Teams of two investigators selected eligible RCTs working independently and extracted information using …

Authors

Briel M; Olu KK; von Elm E; Kasenda B; Alturki R; Agarwal A; Bhatnagar N; Schandelmaier S

Journal

Journal of Clinical Epidemiology, Vol. 80, , pp. 8–15

Publisher

Elsevier

Publication Date

December 2016

DOI

10.1016/j.jclinepi.2016.07.016

ISSN

0895-4356