Journal article
Lower Pill Burden and Once-Daily Antiretroviral Treatment Regimens for HIV Infection: A Meta-Analysis of Randomized Controlled Trials
Abstract
BACKGROUND: Contemporary antiretroviral treatment regimens are simpler than in the past, with lower pill burden and once-daily dosing frequency common. We performed a meta-analysis of randomized controlled trials (RCTs) to investigate the impact of pill burden and once-daily vs twice-daily dosing on ART adherence and virological outcomes.
METHODS: A literature search of 4 electronic databases through 31 March 2013 was used. RCTs comparing …
Authors
Nachega JB; Parienti J-J; Uthman OA; Gross R; Dowdy DW; Sax PE; Gallant JE; Mugavero MJ; Mills EJ; Giordano TP
Journal
Clinical Infectious Diseases, Vol. 58, No. 9, pp. 1297–1307
Publisher
Oxford University Press (OUP)
Publication Date
May 1, 2014
DOI
10.1093/cid/ciu046
ISSN
1058-4838