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Cytoadherence in paediatric malaria: ABO blood...
Journal article

Cytoadherence in paediatric malaria: ABO blood group, CD36, and ICAM1 expression and severe Plasmodium falciparum infection

Abstract

As a leading cause of childhood mortality worldwide, selection pressure by Plasmodium falciparum continues to shape the human genome. Severe disturbances within the microcirculation result from the adhesion of infected erythrocytes to host receptors on monocytes, platelets, and endothelium. In this prospective study, we compared expression of all major host cytoadhesion receptors among Ugandan children presenting with uncomplicated malaria …

Authors

Cserti‐Gazdewich CM; Dhabangi A; Musoke C; Ssewanyana I; Ddungu H; Nakiboneka‐Ssenabulya D; Nabukeera‐Barungi N; Mpimbaza A; Dzik WH

Journal

British Journal of Haematology, Vol. 159, No. 2, pp. 223–236

Publisher

Wiley

Publication Date

October 2012

DOI

10.1111/bjh.12014

ISSN

0007-1048