Journal article
Increased neutrophil elastase activity in cigarette smokers.
Abstract
We compared plasma levels of the neutrophil elastase-derived fibrinopeptide A-alpha-1-21 in healthy cigarette smokers with those in nonsmokers. The mean A-alpha-1-21 concentration was fivefold higher (95% confidence interval [CI], 3.0 to 9.6) in ten cigarette smokers than in 20 healthy nonsmokers (2.0 nmol/L compared with 0.4 nmol/L; p less than 0.0001). To evaluate the acute effect of smoking on enzyme activity, a second group of ten smokers …
Authors
WEITZ JI; CROWLEY KA; LANDMAN SL; LIPMAN BI; YU J
Journal
Annals of Internal Medicine, Vol. 107, No. 5, pp. 680–682
Publisher
American College of Physicians
Publication Date
November 1, 1987
DOI
10.7326/0003-4819-107-5-680
ISSN
1056-8751