Mechanism of Mu DNA transposition Journal Articles

abstract

• AbstractThe study of Mu DNA transposition in vitro has resulted in a much better understanding of the biochemical details of the transposition process. An early step in transposition is the generation of a 5th structure which is the product of the strand‐tansfer reaction. The polarity of the strand transfer has been determined and substantial progress has been made on the role of the individual proteins. Moreover, the strand‐transfer reaction is mediated by stable protein–DNA complexes, or transposomes, and the reaction can be divided into two sequential steps. The role of the transposomes and the requirement for a supercoiled Mu DNA substrate are also discussed.

authors

• Chaconas, George
• Surette, Michael

status

• published 

publication date

• December 1988

has subject area

• 06 Biological Sciences (FoR)
• 11 Medical and Health Sciences (FoR)
• 17 Psychology and Cognitive Sciences (FoR)
• DNA Transposable Elements (MeSH)
• DNA, Bacterial (MeSH)
• Developmental Biology (Science Metrix)
• Escherichia coli (MeSH)
• Genes, Bacterial (MeSH)

published in

• BioEssays  Journal

keywords

• DNA Transposable Elements
• DNA, Bacterial
• Escherichia coli
• Genes, Bacterial

Digital Object Identifier (DOI)

• 10.1002/bies.950090606

PubMed ID

• 2853943

start page

• 205

end page

• 208

volume

• 9

issue

• 6