Mechanism of Mu DNA transposition

Abstract The study of Mu DNA transposition in vitro has resulted in a much better understanding of the biochemical details of the transposition process. An early step in transposition is the generation of a 5th structure which is the product of the strand‐tansfer reaction. The polarity of the strand transfer has been determined and substantial progress has been made on the role of the individual proteins. Moreover, the strand‐transfer reaction …