Journal article
Fatty acid oxidation and triacylglycerol hydrolysis are enhanced after chronic leptin treatment in rats
Abstract
Leptin acutely increases fatty acid (FA) oxidation and triacylglycerol (TG) hydrolysis and decreases TG esterification in oxidative rodent muscle. However, the effects of chronic leptin administration on FA metabolism in skeletal muscle have not been examined. We hypothesized that chronic leptin treatment would enhance TG hydrolysis as well as the capacity to oxidize FA in soleus (SOL) muscle. Female Sprague-Dawley rats were infused for 2 wk …
Authors
Steinberg GR; Bonen A; Dyck DJ
Journal
AJP Endocrinology and Metabolism, Vol. 282, No. 3, pp. e593–e600
Publisher
American Physiological Society
Publication Date
March 1, 2002
DOI
10.1152/ajpendo.00303.2001
ISSN
0193-1849