Journal article
Flumazenil has an anxiolytic effect in simulated stress
Abstract
This study was designed to test whether or not flumazenil (1 mg IV) would change levels of anxiety induced by simulation of public speaking (PSS). Forty normal volunteers were randomly allocated in a parallel groups design to treatment with flumazenil or placebo (double-blind) and one of two stress conditions (PSS/control task). PSS increased anxiety and flumazenil antagonized this effect. The anxiolytic activity of flumazenil was particularly …
Authors
Kapczinski F; Curran HV; Gray J; Lader M
Journal
Psychopharmacology, Vol. 114, No. 1, pp. 187–189
Publisher
Springer Nature
Publication Date
February 1994
DOI
10.1007/bf02245463
ISSN
0033-3158