Journal article
Increased serum glial cell line-derived neurotrophic factor immunocontent during manic and depressive episodes in individuals with bipolar disorder
Abstract
Glial cell line-derived neurotrophic factor (GDNF) is a neurotrophic factor from the transforming growth factor beta family, which plays a role in the development and function of hippocampal cells. Preclinical studies suggest that changes in neurotrophic growth factor systems might be involved in the pathophysiology of mood disorders including bipolar disorder (BD) [E.J. Nestler, M. Barrot, R.J. DiLeone, A.J. Eisch, S.J. Gold, L.M. Monteggia, …
Authors
Rosa AR; Frey BN; Andreazza AC; Ceresér KM; Cunha ABM; Quevedo J; Santin A; Gottfried C; Gonçalves CA; Vieta E
Journal
Neuroscience Letters, Vol. 407, No. 2, pp. 146–150
Publisher
Elsevier
Publication Date
10 2006
DOI
10.1016/j.neulet.2006.08.026
ISSN
0304-3940