Journal article
Effects of a gastrin-releasing peptide receptor antagonist on d-amphetamine-induced oxidative stress in the rat brain
Abstract
Previous studies have suggested that bipolar disorder may be associated with oxidative stress. Administration of d-amphetamine (AMPH) has been put forward as an animal model of mania, and has shown to increase oxidative stress parameters in the rat brain. Thus, we have used the gastrin-releasing peptide receptor antagonist [D-Tpi6Leu13psi (CH2NH)-Leu14] bombesin (RC-3095) as a pharmacological tool to investigate the role of bombesin-like …
Authors
Valvassori SS; Moretti M; Kauer-Sant’Anna M; Roesler R; Petronilho F; Schwartsmann G; Kapczinski F; Dal-Pizzol F; Quevedo J
Journal
Journal of Neural Transmission, Vol. 117, No. 3, pp. 309–316
Publisher
Springer Nature
Publication Date
March 2010
DOI
10.1007/s00702-010-0373-z
ISSN
0300-9564