Journal article
Cannabidiol Exposure During Neuronal Differentiation Sensitizes Cells Against Redox-Active Neurotoxins
Abstract
Cannabidiol (CBD), one of the most abundant Cannabis sativa-derived compounds, has been implicated with neuroprotective effect in several human pathologies. Until now, no undesired side effects have been associated with CBD. In this study, we evaluated CBD’s neuroprotective effect in terminal differentiation (mature) and during neuronal differentiation (neuronal developmental toxicity model) of the human neuroblastoma SH-SY5Y cell line. A …
Authors
Schönhofen P; de Medeiros LM; Bristot IJ; Lopes FM; De Bastiani MA; Kapczinski F; Crippa JAS; Castro MAA; Parsons RB; Klamt F
Journal
Molecular Neurobiology, Vol. 52, No. 1, pp. 26–37
Publisher
Springer Nature
Publication Date
August 2015
DOI
10.1007/s12035-014-8843-1
ISSN
0893-7648