Optimization of Batch Operating Policies. Part II. Incorporating Process Constraints and Industrial Applications

In the first part of this series [Ind. Eng. Chem. Res. 2006, 45, 7856−7866], data-driven approaches, based on partial least squares (PLS) models built from historical batch data, were used to find optimal batch operating trajectories that would yield a desired vector of final product quality attributes. The method allowed for the inclusion of univariate and multivariate constraints on the set of desired final product quality attributes and …