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Comparison of the effects of substance P,...
Journal article

Comparison of the effects of substance P, neurokinin A, physalaemin and eledoisin in facilitating a nociceptive reflex in the rat

Abstract

The postulated existence of different types of tachykinin receptor in the spinal cord provided the basis for the present study; substance P, neurokinin A, eledoisin and physalaemin were administered intrathecally in the awake, restrained rat to compare their effects on reaction time in the tail-flick test. Each peptide was delivered via a chronically implanted subdural catheter to the lower lumbar vertebral level of the spinal cord. Intrathecal …

Authors

Cridland RA; Henry JL

Journal

Brain Research, Vol. 381, No. 1, pp. 93–99

Publisher

Elsevier

Publication Date

August 1986

DOI

10.1016/0006-8993(86)90694-3

ISSN

0006-8993