Journal article
DNA Aptamer Folding on Gold Nanoparticles: From Colloid Chemistry to Biosensors
Abstract
We have investigated the effect of the folding of DNA aptamers on the colloidal stability of gold nanoparticles (AuNPs) to which an aptamer is tethered. On the basis of the studies of two different aptamers (adenosine aptamer and K+ aptamer), we discovered a unique colloidal stabilization effect associated with aptamer folding: AuNPs to which folded aptamer structures are attached are more stable toward salt-induced aggregation than those …
Authors
Zhao W; Chiuman W; Lam JCF; McManus SA; Chen W; Cui Y; Pelton R; Brook MA; Li Y
Journal
Journal of the American Chemical Society, Vol. 130, No. 11, pp. 3610–3618
Publisher
American Chemical Society (ACS)
Publication Date
March 1, 2008
DOI
10.1021/ja710241b
ISSN
0002-7863