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Rapid and Efficient Assembly of Functional...
Journal article

Rapid and Efficient Assembly of Functional Silicone Surfaces Protected by PEG: Cell Adhesion to Peptide-Modified PDMS

Abstract

While silicone elastomers generally have excellent biomaterials properties, their hydrophobicity can elicit undesired local biological responses through adsorption and denaturation of proteins. Surface-bound poly(ethylene glycol) (PEG) can ameliorate the situation by preventing contact between the external biology and the silicone elastomer. It is further possible to manipulate the biocompatibility of the surface by linking peptides, proteins …

Authors

Mikhail AS; Ranger JJ; Liu L; Longenecker R; Thompson DB; Sheardown HD; Brook MA

Journal

Journal of Biomaterials Science Polymer Edition, Vol. 21, No. 6-7, pp. 821–842

Publisher

Taylor & Francis

Publication Date

January 2010

DOI

10.1163/156856209x445311

ISSN

0920-5063