Journal article
Measurement of intracellular chloride ion concentration in ICC in situ and in explant culture
Abstract
BACKGROUND: Chloride channels are proposed to play a central role in the electrical pacemaking mechanism of interstitial cells of Cajal (ICC). A key unknown factor in the consideration of this role is the chloride equilibrium potential (E(Cl)), as determined by the relative concentrations of intra- ([Cl(-)](i)) and extracellular ([Cl(-)](o)) chloride ions.
METHODS: To calculate the E(Cl) of ICC, [Cl(-)](i) was measured with the fluorescent …
Authors
Zhu Y; Parsons SP; Huizinga JD
Journal
Neurogastroenterology & Motility, Vol. 22, No. 6, pp. 704–709
Publisher
Wiley
Publication Date
6 2010
DOI
10.1111/j.1365-2982.2010.01501.x
ISSN
1350-1925