Journal article
Cholinergic signalling-regulated KV7.5 currents are expressed in colonic ICC-IM but not ICC-MP
Abstract
Interstitial cells of Cajal (ICC) and the enteric nervous system orchestrate the various rhythmic motor patterns of the colon. Excitation of ICC may evoke stimulus-dependent pacemaker activity and will therefore have a profound effect on colonic motility. The objective of the present study was to evaluate the potential role of K+ channels in the regulation of ICC excitability. We employed the cell-attached patch clamp technique to assess single …
Authors
Wright GWJ; Parsons SP; Loera-Valencia R; Wang X-Y; Barajas-López C; Huizinga JD
Journal
Pflügers Archiv - European Journal of Physiology, Vol. 466, No. 9, pp. 1805–1818
Publisher
Springer Nature
Publication Date
September 2014
DOI
10.1007/s00424-013-1425-7
ISSN
0031-6768