Journal article
s‐CARBOXYMETHYLCYSTEINE INHIBITS CARBACHOL‐INDUCED CONSTRICTION OF EPITHELIUM‐DENUDED RAT AND HUMAN AIRWAY PREPARATIONS
Abstract
1. The effects of s-carboxymethyl-L-cysteine (S-CMC), either administered orally to rats or incubated with tissue preparations from rats and humans, on isometric contractions of tracheal smooth muscle were investigated in the present study using an improved in vitro model of tracheal tube or ring preparations. The involvement of the tracheal epithelium in the observed effects was also investigated. 2. The experimental model permitted selective …
Authors
Pavlovic D; Frieling H; Usichenko T; Nedeljkov V; Nafissi T; Lehmann C; Aubier M; Wendt M
Journal
Clinical and Experimental Pharmacology and Physiology, Vol. 35, No. 5‐6, pp. 663–669
Publisher
Wiley
Publication Date
May 2008
DOI
10.1111/j.1440-1681.2007.04857.x
ISSN
0305-1870