Journal article
Markers of Skeletal Muscle Mitochondrial Function and Lipid Accumulation Are Moderately Associated with the Homeostasis Model Assessment Index of Insulin Resistance in Obese Men
Abstract
Lower skeletal muscle mitochondrial oxidative phosphorylation capacity (OXPHOS) and intramyocellular lipid (IMCL) accumulation have been implicated in the etiology of insulin resistance (IR) in obesity. The purpose of this study was to examine the impact of endurance exercise on biochemical and morphological measures of IMCL and mitochondrial content, and their relationship to IR in obese individuals. We examined mitochondrial content (subunit …
Authors
Samjoo IA; Safdar A; Hamadeh MJ; Glover AW; Mocellin NJ; Santana J; Little JP; Steinberg GR; Raha S; Tarnopolsky MA
Journal
PLOS ONE, Vol. 8, No. 6,
Publisher
Public Library of Science (PLoS)
Publication Date
2013
DOI
10.1371/journal.pone.0066322
ISSN
1932-6203