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Total thrombin‐activatable fibrinolysis inhibitor...
Journal article

Total thrombin‐activatable fibrinolysis inhibitor (TAFI) antigen and pro‐TAFI in patients with haemophilia A

Abstract

Pro-thrombin-activatable fibrinolysis inhibitor (pro-TAFI), also known as TAFI, procarboxypeptidase U, or procarboxypeptidase B, is a relatively recently described plasma glycoprotein synthesized in the liver. It can be catalysed into its active form, TAFI (TAFIa, carboxypeptidase U or B) by a complex of thrombin/thrombomodulin. TAFI can potentially inhibit fibrinolysis by removing carboxyterminal lysine residues from partially degraded fibrin, …

Authors

Antovic J; Schulman S; Eelde A; Blombäck M

Journal

Haemophilia, Vol. 7, No. 6, pp. 557–560

Publisher

Wiley

Publication Date

November 12, 2001

DOI

10.1046/j.1365-2516.2001.00571.x

ISSN

1351-8216