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Enoxaparin Versus Dabigatran or Rivaroxaban for...
Journal article

Enoxaparin Versus Dabigatran or Rivaroxaban for Thromboprophylaxis After Hip or Knee Arthroplasty

Abstract

BACKGROUND: Dabigatran and rivaroxaban are novel oral anticoagulants approved for prevention of venous thromboembolism after hip or knee arthroplasty. However, information assessing clinically important efficacy and bleeding outcomes of these 2 new agents versus low-molecular-weight heparin (enoxaparin) is lacking. METHODS AND RESULTS: We separately pooled efficacy and safety data from 6 phase III randomized trials (18 405 participants) …

Authors

Huisman MV; Quinlan DJ; Dahl OE; Schulman S

Journal

Circulation Cardiovascular Quality and Outcomes, Vol. 3, No. 6, pp. 652–660

Publisher

Wolters Kluwer

Publication Date

November 2010

DOI

10.1161/circoutcomes.110.957712

ISSN

1941-7713