Journal article
A Benefit-Risk Assessment of Dabigatran in the Prevention of Venous Thromboembolism in Orthopaedic Surgery
Abstract
Dabigatran etexilate is a novel orally administered anticoagulant that exerts its action through reversible direct thrombin inhibition. This anticoagulant has been approved for prophylaxis against venous thromboembolism (VTE) after hip or knee arthroplasty, and in a few countries also for atrial fibrillation. This article reviews the efficacy and safety of dabigatran for the prophylaxis of VTE-indication compared with data on the most common …
Authors
Schulman S; Majeed A
Journal
Drug Safety, Vol. 34, No. 6, pp. 449–463
Publisher
Springer Nature
Publication Date
June 2011
DOI
10.2165/11587290-000000000-00000
ISSN
0114-5916