Journal article
Increased fetal loss in women with heritable thrombophilia
Abstract
BACKGROUND: A successful outcome of pregnancy requires an efficient uteroplacental vascular system. Since this system may be compromised by disorders of haemostasis associated with a prothrombotic state, we postulated that maternal thrombophilia might be a risk factor for fetal loss. We studied the relation between heritable thrombophilic defects and fetal loss in a cohort of women with factor V Leiden or deficiency of antithrombin, protein C, …
Authors
Preston F; Rosendaal; Walker I; Briët E; Berntorp E; Conard J; Fontcuberta J; Makris M; Mariani G; Noteboom W
Journal
The Lancet, Vol. 348, No. 9032, pp. 913–916
Publisher
Elsevier
Publication Date
October 1996
DOI
10.1016/s0140-6736(96)04125-6
ISSN
0140-6736