Journal article
Combining oncolytic virotherapy and tumour vaccination
Abstract
The interactions between the immune system, a malignant tumour and an oncolytic virus are complex and poorly understood. For oncolytic viruses to become successful therapeutics we need to better understand these interactions and identify strategies to take advantage of defects in the innate immune response within tumours and avoid cellular anti-viral responses while capitalizing on anti-tumoural immunity. In this review we will discuss the …
Authors
Bridle BW; Hanson S; Lichty BD
Journal
Cytokine & Growth Factor Reviews, Vol. 21, No. 2-3, pp. 143–148
Publisher
Elsevier
Publication Date
April 2010
DOI
10.1016/j.cytogfr.2010.02.009
ISSN
1359-6101