Journal article
Fluoroquinolone therapy and idiosyncratic acute liver injury: a population-based study
Abstract
BACKGROUND: Although fluoroquinolones are sometimes associated with mild, transient elevations in aminotransferase levels, serious acute liver injury is uncommon. Regulatory warnings have identified moxifloxacin as presenting a particular risk of hepatotoxicity. Thus, we examined the risk of idiosyncratic acute liver injury associated with the use of moxifloxacin relative to other selected antibiotic agents.
METHODS: We conducted a …
Authors
Paterson JM; Mamdani MM; Manno M; Juurlink DN
Journal
Canadian Medical Association Journal, Vol. 184, No. 14, pp. 1565–1570
Publisher
Joule
Publication Date
October 2, 2012
DOI
10.1503/cmaj.111823
ISSN
0820-3946