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Association Between Incretin-Based Drugs and the...
Journal article

Association Between Incretin-Based Drugs and the Risk of Acute Pancreatitis

Abstract

IMPORTANCE: The association between incretin-based drugs, such as dipeptidyl peptidase 4 (DPP-4) inhibitors and glucagon-like peptide 1 (GLP-1) agonists, and acute pancreatitis is controversial. OBJECTIVE: To determine whether the use of incretin-based drugs, compared with the use of 2 or more other oral antidiabetic drugs, is associated with an increased risk of acute pancreatitis.

Authors

Azoulay L; Filion KB; Platt RW; Dahl M; Dormuth CR; Clemens KK; Durand M; Hu N; Juurlink DN; Paterson JM

Journal

JAMA Internal Medicine, Vol. 176, No. 10, pp. 1464–1473

Publisher

American Medical Association (AMA)

Publication Date

October 1, 2016

DOI

10.1001/jamainternmed.2016.1522

ISSN

2168-6106