Journal article
The Cardiovascular Safety of Dutasteride
Abstract
PURPOSE: Randomized controlled trials suggest an increased risk of heart failure with dutasteride, which inhibits both the type 1 and type 2 isoforms of 5α-reductase. In contrast, no such association has been suggested for finasteride, which selectively inhibits the type 2 isoform. We investigated the risk of cardiovascular events among patients receiving dutasteride relative to finasteride.
MATERIALS AND METHODS: We performed a population …
Authors
Skeldon SC; Macdonald EM; Law MR; Huang A; Paterson JM; Mamdani MM; Juurlink D
Journal
Journal of Urology, Vol. 197, No. 5, pp. 1309–1314
Publisher
Wolters Kluwer
Publication Date
May 2017
DOI
10.1016/j.juro.2016.11.082
ISSN
0021-0005