Validity of composite end points in clinical trials Journal Articles

abstract

• Use of composite end points as the main outcome in randomised trials can hide wide differences in the individual measures. How should you apply the results to clinical practice?

authors

• Guyatt, Gordon
• Jaeschke, Roman
• Schunemann, Holger
• Montori, Victor M
• Permanyer-Miralda, Gaietà
• Ferreira-González, Ignacio
• Busse, Jason Walter
• Pacheco-Huergo, Valeria
• Bryant, Dianne
• Alonso, Jordi
• Akl, Elie
• Domingo-Salvany, Antònia
• Mills, Edward Joseph
• others

status

• published 

publication date

• 2005

has subject area

• 1103 Clinical Sciences (FoR)
• 1117 Public Health and Health Services (FoR)
• Endpoint Determination (MeSH)
• General & Internal Medicine (Science Metrix)
• Humans (MeSH)
• Randomized Controlled Trials as Topic (MeSH)
• Sensitivity and Specificity (MeSH)

published in

• The BMJ  Journal

keywords

• Endpoint Determination
• Humans
• Randomized Controlled Trials as Topic
• Sensitivity and Specificity

Digital Object Identifier (DOI)

• 10.1136/bmj.330.7491.594

start page

• 594

end page

• 596

volume

• 330

issue

• 7491