RENAL DYSFUNCTION IN CADMIUM SMELTERS: RELATION TO IN-VIVO LIVER AND KIDNEY CADMIUM CONCENTRATIONS Academic Article uri icon

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abstract

  • Biochemical indicators of renal dysfunction have been compared with liver and kidney cadmium levels measured by neutron activation analysis in a group of 37 cadmium smelters. Higher than normal concentrations of cadmium in the liver reflect past exposure; they were associated with evidence of renal dysfunction in workers exposed to cadmium for more than 10 years. A small group of 6 workers exposed to cadmium for only a short time (mean = 4.6 years) had high hepatic cadmium concentrations but normal renal function. Longitudinal studies are required to establish the natural history of renal dysfunction following cadmium accumulation in industrial workers.

authors

  • Gompertz, D
  • Fletcher, JG
  • Perkins, J
  • Smith, NJ
  • Chettle, David
  • Mason, H
  • Scott, MC
  • Topping, MD
  • Blindt, M

publication date

  • May 1983