Journal article
Mammary Gland Morphology in Sprague-Dawley Rats following Treatment with an Organochlorine Mixture in Utero and Neonatal Genistein
Abstract
In a related reproductive toxicology study designed to investigate the effects of in utero exposure to environmental toxicants and potential interaction with postnatal genistein, gross enlargement of thoracic mammary glands was observed in female offspring at 200 days of age. Therefore, the objective of this study was to analyze the effect of in utero exposure to a mixture of toxicants on mammary gland morphology. Time-mated Sprague-Dawley rats …
Authors
Foster WG; Younglai EV; Boutross-Tadross O; Hughes CL; Wade MG
Journal
Toxicological Sciences, Vol. 77, No. 1, pp. 91–100
Publisher
Oxford University Press (OUP)
Publication Date
1 2004
DOI
10.1093/toxsci/kfg247
ISSN
1096-6080
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Administration, OralAnimalsAnimals, NewbornDrug CombinationsDrug SynergismFemaleGenisteinGrowth InhibitorsHydrocarbons, ChlorinatedInjections, SubcutaneousInsecticidesMammary Glands, AnimalMammary Neoplasms, AnimalMaternal ExposurePrecancerous ConditionsPregnancyPrenatal Exposure Delayed EffectsRatsRats, Sprague-Dawley