Inflammatory and growth factor response to continuous and intermittent exercise in youth with cystic fibrosis

BACKGROUND: Children with cystic fibrosis (CF) tend to suffer from chronic systemic inflammation and may have impaired growth associated with muscle catabolism. Therefore, investigating which type of exercise can elicit an anabolic response with minimal inflammation is of clinical value. METHODS: Twelve children with CF (mean±SD; age: 14.7±2.3 years, predicted FEV(1): 90.0±21.6%) and biological age-matched controls (age: 13.9±2.1 years) …