Journal article
Abundance of heteronuclear and messenger RNA for internal Ca pump in stomach smooth muscle and myocardium
Abstract
The sarcoplasmic reticulum Ca pump gene SERCA2 is alternatively spliced to express mRNA encoding the protein SERCA2a in heart and SERCA2b in stomach smooth muscle. The expression of SERCA2 protein in heart is 70 +/- 10 fold that in stomach smooth muscle. To understand the mechanism underlying this tissue difference in the expression level, a comparison is made of their mRNA and heteronuclear RNA (hn-RNA) contents. A 72 bp intron present in the …
Authors
Khan I; Grover AK
Journal
Cell Calcium, Vol. 14, No. 1, pp. 17–23
Publisher
Elsevier
Publication Date
January 1993
DOI
10.1016/0143-4160(93)90014-w
ISSN
0143-4160