Non-invasive determination of transcatheter pressure gradient in stenotic aortic valves: An analytical model

Aortic stenosis (AS), in which the opening of the aortic valve is narrowed, is the most common valvular heart disease. Cardiac catheterization is considered the reference standard for definitive evaluation of AS severity, based on instantaneous systolic value of transvalvular pressure gradient (TPG). However, using invasive cardiac catheterization might carry high risks knowing that undergoing multiple cardiac catheterizations for follow-up in …