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The ontogeny of NADPH-diaphorase neurons in...
Journal article

The ontogeny of NADPH-diaphorase neurons in serum-free striatal cultures parallels in vivo development

Abstract

Nitric oxide synthase is co-localized with somatostatin and neuropeptide Y in a subpopulation of striatal interneurons that stain selectively for NADPH-diaphorase. We studied the ontogeny of diaphorase-positive neurons in striatal serum-free cultures derived from 15-16-day-old CD1 mice. NADPH-diaphorase staining was detected as early as embryological day 18 in vivo and day 5 in vitro. Over the next seven days the number of neurons staining for …

Authors

Garside S; Woulfe J; Mazurek MF

Journal

Neuroscience, Vol. 76, No. 4, pp. 1221–1230

Publisher

Elsevier

Publication Date

1 1997

DOI

10.1016/s0306-4522(96)00415-0

ISSN

0306-4522