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Journal article

Proton magnetic resonance spectroscopy of prefrontal white matter in psychotropic naïve children and adolescents with obsessive–compulsive disorder

Abstract

Obsessive-compulsive disorder (OCD) has a typical onset during childhood or adolescence. Although recent in-vivo proton magnetic resonance spectroscopy ((1)H-MRS) studies report gray matter metabolite abnormalities in children and adolescents with OCD, there are no existing (1)H-MRS studies that measure white matter (WM) metabolite levels in this population. In the present study, we measured metabolite levels in the left and right prefrontal WM …

Authors

Weber AM; Soreni N; Stanley JA; Greco A; Mendlowitz S; Szatmari P; Schachar R; Mannasis K; Pires P; Swinson R

Journal

Psychiatry Research, Vol. 222, No. 1-2, pp. 67–74

Publisher

Elsevier

Publication Date

April 2014

DOI

10.1016/j.pscychresns.2014.02.004

ISSN

0165-1781