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Systematic reviews and meta‐analyses of benefits...
Journal article

Systematic reviews and meta‐analyses of benefits and harms of cryotherapy, LEEP, and cold knife conization to treat cervical intraepithelial neoplasia

Abstract

BACKGROUND: Cervical intraepithelial neoplasia (CIN) stage 2-3 is a premalignant lesion that can progress to cervical cancer in 10-20 years if untreated. OBJECTIVES: To conduct systematic reviews of randomized and nonrandomized studies for effects of cryotherapy, loop electrosurgical excision procedure (LEEP), and cold knife conization (CKC) as treatment for CIN 2-3.

Authors

Santesso N; Mustafa RA; Wiercioch W; Kehar R; Gandhi S; Chen Y; Cheung A; Hopkins J; Khatib R; Ma B

Journal

International Journal of Gynecology & Obstetrics, Vol. 132, No. 3, pp. 266–271

Publisher

Wiley

Publication Date

March 2016

DOI

10.1016/j.ijgo.2015.07.026

ISSN

0020-7292