Genetic sonography after first‐trimester Down...

Abstract

OBJECTIVE: Approximately 90% of Down syndrome cases are detected during first-trimester screening. We aimed to determine the potential effectiveness of second-trimester genetic sonography as a sequential screen for Down syndrome. METHODS: In this simulation study, published statistical parameters for first-trimester free beta-human chorionic gonadotropin, pregnancy-associated plasma protein-A and nuchal translucency thickness, and …

Authors

Krantz DA; Hallahan TW; Macri VJ; Macri JN

Journal

Ultrasound in Obstetrics and Gynecology, Vol. 29, No. 6, pp. 666–670

Publisher

Wiley

Publication Date

June 2007

DOI

10.1002/uog.4029

ISSN

0960-7692

Associated Experts

Joseph Macri

Associate Professor, Faculty of Health Sciences

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Labels

Fields of Research (FoR)

3215 Reproductive medicine 32 Biomedical and Clinical Sciences 3202 Clinical sciences

Medical Subject Headings (MeSH)

Biomarkers Chorionic Gonadotropin Down Syndrome Female Femur Humans Humerus Intestine, Large Nuchal Translucency Measurement Pregnancy Pregnancy Trimester, First Pregnancy Trimester, Second Pregnancy-Associated Plasma Protein-A Prenatal Diagnosis Risk Factors Ultrasonography, Prenatal

Genetic sonography after first‐trimester Down syndrome screening