Processed residual pump blood in cardiac surgery: the Processed Residual Blood in Cardiac surgery trial

BACKGROUND: Processing residual cardiopulmonary bypass (CPB) volume via ultrafiltration may improve hemostasis and reduce transfusion through clearing activated complement, activated coagulation components, and proinflammatory cytokines. We sought to establish if processing residual CPB volume with ultrafiltration reduces homologous blood transfusion and bleeding. STUDY DESIGN AND METHODS: Adult patients undergoing isolated coronary artery …