La Crosse Encephalitis Surveillance using Single Versus Paired Serologic Testing Academic Article

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abstract

We evaluated the validity of single versus paired serologic testing for La Crosse virus (LACV) encephalitis surveillance. Compared with paired serology, a single positive IgG or IgM immunoflourescent antibody titre appears useful for LACV encephalitis surveillance with sensitivity, 75%; specificity, 98%; positive predictive value, 95%; and overall test efficiency 92%.

authors

Murphree, R
Dunn, James
Schaffner, W
Jones, TF

status

published

publication date

May 2012

has subject area

06 Biological Sciences (FoR)
07 Agricultural and Veterinary Sciences (FoR)
11 Medical and Health Sciences (FoR)
Adolescent (MeSH)
Adult (MeSH)
Aged (MeSH)
Aged, 80 and over (MeSH)
Animals (MeSH)
Antibodies, Viral (MeSH)
Antigens, Viral (MeSH)
Child (MeSH)
Child, Preschool (MeSH)
Encephalitis, California (MeSH)
Female (MeSH)
Fluorescent Antibody Technique (MeSH)
Hospitalization (MeSH)
Humans (MeSH)
Immunoglobulin G (MeSH)
Immunoglobulin M (MeSH)
Infant (MeSH)
La Crosse virus (MeSH)
Male (MeSH)
Middle Aged (MeSH)
Predictive Value of Tests (MeSH)
Reproducibility of Results (MeSH)
Sentinel Surveillance (MeSH)
Serologic Tests (MeSH)
Tennessee (MeSH)
Veterinary Sciences (Science Metrix)
Young Adult (MeSH)

published in

Zoonoses and Public Health Journal