Journal article
Blood pressure-dependent and independent effects of agents that inhibit the renin–angiotensin system
Abstract
OBJECTIVES: To evaluate the blood pressure-dependent and independent effects of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) on major cardiovascular events.
METHODS: Using data from 26 large-scale trials comparing an ACEI or an ARB with placebo or another drug class, meta-regression analyses were conducted in which treatment-specific relative risks for major cause-specific outcomes [stroke, major …
Authors
Turnbull F; Neal B; Pfeffer M; Kostis J; Algert C; Woodward M; Chalmers J; Zanchetti A; MacMahon S
Journal
Journal of Hypertension, Vol. 25, No. 5, pp. 951–958
Publisher
Wolters Kluwer
Publication Date
May 2007
DOI
10.1097/hjh.0b013e3280bad9b4
ISSN
0263-6352