Journal article
Can PPARγ agonists have a role in the management of obesity-related hypertension?
Abstract
Peroxisome proliferator-activated receptors (PPAR) are ligand-activated transcription factors belonging to the nuclear hormone receptor superfamily. PPARgamma is the most extensively studied amongst the three subtypes (alpha, delta and gamma). This receptor is a key modulator of lipid and glucose homeostasis and is predominantly expressed in adipose tissue. Expression of PPARgamma is also found in non-adipose tissues including heart, kidney, …
Authors
Chetty VT; Sharma AM
Journal
Vascular Pharmacology, Vol. 45, No. 1, pp. 46–53
Publisher
Elsevier
Publication Date
July 2006
DOI
10.1016/j.vph.2005.11.010
ISSN
1537-1891