Journal article
A Trial of Wound Irrigation in the Initial Management of Open Fracture Wounds
Abstract
BACKGROUND: The management of open fractures requires wound irrigation and débridement to remove contaminants, but the effectiveness of various pressures and solutions for irrigation remains controversial. We investigated the effects of castile soap versus normal saline irrigation delivered by means of high, low, or very low irrigation pressure.
METHODS: In this study with a 2-by-3 factorial design, conducted at 41 clinical centers, we randomly …
Authors
Bhandari M; Jeray KJ; Petrisor BA; Devereaux PJ; Heels-Ansdell D; Schemitsch EH; Anglen J; Della Rocca GJ; Jones C; Kreder H
Journal
New England Journal of Medicine, Vol. 373, No. 27, pp. 2629–2641
Publisher
Massachusetts Medical Society
Publication Date
December 31, 2015
DOI
10.1056/nejmoa1508502
ISSN
0028-4793