Journal article
Frequency and clinical consequences of extremely high maternal serum PAPP‐A levels
Abstract
A multicentre study was carried out to determine the frequency and clinical consequences of extremely high maternal serum pregnancy-associated plasma protein (PAPP)-A. There was a total of 79 pregnancies with PAPP-A exceeding 5.0 multiples of the gestation-specific median in a series of 46 776 pregnancies tested (0.2%) at the 7 collaborating centres. Five pregnancies were lost to follow-up, one miscarried and one with Noonan's syndrome was …
Authors
Cuckle H; Arbuzova S; Spencer K; Crossley J; Barkai G; Krantz D; Muller F; Nikolenko M; Aitken D; Hallahan T
Journal
Prenatal Diagnosis, Vol. 23, No. 5, pp. 385–388
Publisher
Wiley
Publication Date
May 2003
DOI
10.1002/pd.600
ISSN
0197-3851