Journal article
Cellular compensatory mechanisms in the CNS of dysmyelinated rats.
Abstract
Loss or absolute lack of myelin in the CNS results in remarkable compensation at the cellular level. In this study on the natural progression of neuropathology in the CNS in 2 related but distinct long-lived dysmyelinated rats, total lack of myelin was associated with remarkable glial cell proliferation and ineffective myelinating activity throughout life in Long Evans Bouncer (LE-bo) rats; conversely, in Long Evans Shaker (LES) rats, futile …
Authors
Kwiecien JM
Journal
Journal of the American Association for Laboratory Animal Science, Vol. 60, No. 3, pp. 205–217
Publication Date
6 2010
ISSN
1559-6109