The Effects of Dietary Sodium on Hypertension and Stroke Development in Female Stroke-Prone Spontaneously Hypertensive Rats

Previous studies on male stroke-prone spontaneously hypertensive rats (SHRSP) have shown that a high-salt diet accelerated the onset of hypertension and stroke, resulting in an increased mortality rate at a younger age. The purpose of this study was to examine whether a similar effect is present in female SHRSP. After weaning at 4 weeks of age, 32 female SHRSP were placed on a Japanese-style rat diet containing either 0.3% NaCl or 4% NaCl. …