Journal article
Antiepileptic drugs, hepatic enzyme induction and raised serum alkaline phosphatase isoenzymes.
Abstract
Thirteen patients with epilepsy on long-term antiepileptic drug therapy and who had a persistently raised serum alkaline phosphatase (ALP) activity were investigated biochemically. Twelve patients had a raised liver ALP-isoenzyme activity and in nine of these the bone ALP-isoenzyme activity was normal. Gamma-glutamyl transferase (gamma GT) levels were raised in 12 patients. Two patients were hypoglycaemic. One patient fitted the biochemical …
Authors
Nijhawan R; Wierzbicki AS; Tozer R; Lascelles PT; Patsalos PN
Journal
Clinical pharmacology research, Vol. 10, No. 6, pp. 319–323
Publication Date
1990
ISSN
0251-1649