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The Probiotic VSL#3 Has Anti-inflammatory Effects...
Journal article

The Probiotic VSL#3 Has Anti-inflammatory Effects and Could Reduce Endoscopic Recurrence After Surgery for Crohn's Disease

Abstract

BACKGROUND & AIMS: Probiotic formulations of single species of bacteria have not been effective in preventing the recurrence of Crohn's disease after surgery. We investigated the ability of VSL#3, a mixture of 8 different bacterial probiotic species, to prevent Crohn's disease recurrence after surgery in a multicenter, randomized, double-blind, placebo-controlled trial. METHODS: Within 30 days of ileocolonic resection and re-anastomosis, …

Authors

Fedorak RN; Feagan BG; Hotte N; Leddin D; Dieleman LA; Petrunia DM; Enns R; Bitton A; Chiba N; Paré P

Journal

Clinical Gastroenterology and Hepatology, Vol. 13, No. 5, pp. 928–935.e2

Publisher

Elsevier

Publication Date

May 2015

DOI

10.1016/j.cgh.2014.10.031

ISSN

1542-3565